Across TCGA pan-cancer cohorts, SAR1AP3 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated SAR1AP3 data layer.
The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SAR1AP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SAR1AP3 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.
SKCM, HNSC, and MESO are the cancer types where SAR1AP3 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.