Across TCGA pan-cancer cohorts, SAR1AP3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SAR1AP3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SAR1AP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SAR1AP3 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, UCEC, and CHOL are the cancer types where SAR1AP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SAR1AP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.188	.005	4	view →
UCEC	All	III,IV	+0.184	.019	4	view →
CHOL	All	II,III,IV	+0.165	<.001	2	view →
KIRC	Male	II,III,IV	−0.028	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SAR1AP3 RNA expression & survival · all SAR1AP3 data types