SAR1A

Across TCGA patient cohorts, SAR1A protein abundance is significantly associated with the RNA expression of many other genes, with 10,646 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAR1A-associated genes across cancer lineages are PIGH, INTS2, and ALDH3A1. Each is linked with SAR1A in more than 2 cancer types. Because this analysis shows association rather than direction, both SAR1A-to-partner and partner-to-SAR1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAR1A versus PIGH in BRCA, with a Pearson correlation of -0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAR1A→partner) and Y-score (partner→SAR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIGH →	-0.403	-0.179	.008	.003	3	3
BRCA	INTS2 →	-0.549	-0.239	.003	.002	3	3
LSCC	ALDH3A1 →	-2.740	-0.188	<.001	<.001	3	3
BRCA	NEK4 →	-0.487	-0.183	.003	.005	3	3
BRCA	GPD2 →	-0.662	-0.218	.006	.002	3	3
BRCA	CEP68 →	-0.507	-0.232	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,646 associations by consensus.

SAR1A vs PIGH — BRCA

Explore this scatter interactively →