SAR1A

Across TCGA cell cohorts, SAR1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,183 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAR1A-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Regulation of sister chromatid cohesion. Each is linked with SAR1A in more than 12 cancer types. Because this analysis shows association rather than direction, both SAR1A-to-partner and partner-to-SAR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by SAR1A-low versus SAR1A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAR1A→partner) and Y-score (partner→SAR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.139	+0.867	.001	<.001	3	13
BONE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.086	+0.554	<.001	.001	3	12
LUNG_SCLC	Regulation of sister chromatid cohesion →	+0.106	+0.504	<.001	.005	3	11
SOFT_TISSUE	COPII-coated vesicle cargo loading →	+0.098	+0.671	<.001	<.001	3	10
LARGE_INTESTINE	Negative regulation of chromosome segregation →	+0.101	+0.740	<.001	.001	3	10
URINARY_TRACT	Double-strand break repair via nonhomologous end joining →	+0.054	+0.563	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,183 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by SAR1A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →