SAP30BP

Across TCGA patient cohorts, SAP30BP mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAP30BP-associated genes across cancer lineages are EGFR_pY1068, ERK2, and AMPK_pT172. Each is linked with SAP30BP in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP30BP-to-partner and partner-to-SAP30BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by SAP30BP-low versus SAP30BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP30BP→partner) and Y-score (partner→SAP30BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.313	-3.459	.012	.005	3	1
UCEC	ERK2 →	+0.193	+3.459	.046	.005	3	1
UCEC	AMPK_pT172 →	+0.488	+3.169	.018	.019	3	1
UCEC	Rab11 →	-0.164	-2.321	.024	.035	3	1
UCEC	SF2 →	-0.179	-2.308	.001	.036	3	1
UCEC	STAT5a →	+0.547	+2.321	.006	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

EGFR_pY1068 by SAP30BP expression — UCEC

Explore this box plot interactively →