SAP30BP

Across TCGA cell cohorts, SAP30BP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,990 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAP30BP-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Spliceosomal tri-snRNP complex assembly, and Regulation of microtubule cytoskeleton organization. Each is linked with SAP30BP in more than 11 cancer types. Because this analysis shows association rather than direction, both SAP30BP-to-partner and partner-to-SAP30BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by SAP30BP-low versus SAP30BP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP30BP→partner) and Y-score (partner→SAP30BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of beige fat cell differentiation →	+0.188	+0.892	<.001	.002	3	12
URINARY_TRACT	Spliceosomal tri-snRNP complex assembly →	+0.096	+0.537	<.001	.003	3	10
LUNG_NSCLC_LUSC	Regulation of microtubule cytoskeleton organization →	+0.074	+0.686	.002	.005	3	10
URINARY_TRACT	Positive regulation of spindle checkpoint →	+0.189	+0.817	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.189	+0.817	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein-DNA covalent cross-linking repair →	+0.083	+0.655	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,990 associations by consensus.

Negative regulation of beige fat cell differentiation by SAP30BP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →