SAP30BP

Across TCGA cell cohorts, SAP30BP mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAP30BP-associated genes across cancer lineages are CFHR2, HRG, and KAAG1. Each is linked with SAP30BP in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP30BP-to-partner and partner-to-SAP30BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by SAP30BP-low versus SAP30BP-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP30BP→partner) and Y-score (partner→SAP30BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFHR2 →	+0.204	+4.539	<.001	<.001	3	2
BLOOD_Leukemia	HRG →	+0.342	+4.177	<.001	.001	3	1
BLOOD_Leukemia	KAAG1 →	+0.094	+4.177	<.001	.001	3	1
BLOOD_Leukemia	ASZ1 →	+0.098	+3.567	.001	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.163	+3.289	<.001	.009	3	1
BLOOD_Leukemia	KSR2 →	+0.302	+3.798	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CFHR2 by SAP30BP expression — BLOOD_Leukemia

Explore this box plot interactively →