SAP30

Across TCGA patient cohorts, SAP30 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAP30-associated genes across cancer lineages are Myosin-IIa_pS1943, PDCD4, and Rab25. Each is linked with SAP30 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP30-to-partner and partner-to-SAP30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa_pS1943 grouped by SAP30-low versus SAP30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP30→partner) and Y-score (partner→SAP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa_pS1943 →	+0.243	+3.183	.032	.010	3	1
UCEC	PDCD4 →	-0.600	-3.169	.020	.020	3	1
UCEC	Rab25 →	-0.476	-3.169	.008	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Myosin-IIa_pS1943 by SAP30 expression — UCEC

Explore this box plot interactively →