SAP30

Across TCGA cell cohorts, SAP30 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,259 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SAP30-associated GO terms across cancer lineages are Negative regulation of mitotic sister chromatid separation, Negative regulation of sister chromatid segregation, and Regulation of mitotic sister chromatid segregation. Each is linked with SAP30 in more than 15 cancer types. Because this analysis shows association rather than direction, both SAP30-to-partner and partner-to-SAP30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitotic sister chromatid separation grouped by SAP30-low versus SAP30-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP30→partner) and Y-score (partner→SAP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of mitotic sister chromatid separation →	+0.222	+1.133	.001	.009	3	16
OESOPHAGUS	Negative regulation of sister chromatid segregation →	+0.222	+1.133	.001	.009	3	16
OESOPHAGUS	Regulation of mitotic sister chromatid segregation →	+0.181	+1.242	.003	.006	3	16
OESOPHAGUS	Negative regulation of mitotic sister chromatid segregation →	+0.222	+1.133	.001	.009	3	16
OESOPHAGUS	Negative regulation of mitotic metaphase/anaphase transition →	+0.222	+1.133	.001	.009	3	16
UPPER_AERODIGESTIVE_TRACT	Mitotic chromosome condensation →	+0.152	+1.037	.003	.005	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,259 associations by consensus.

Negative regulation of mitotic sister chromatid separation by SAP30 expression — OESOPHAGUS

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