SAP30-DT

Across TCGA pan-cancer cohorts, SAP30-DT RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SAP30-DT data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher SAP30-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SAP30-DT expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

KICH, UVM, and READ are the cancer types where SAP30-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	II,III,IV	0.667	1.000	.001	102	view →
UVM	DFS	Tertile	All	0.284	0.698	.001	84	view →
READ	DFS	Tertile	IV	0.309	0.880	<.001	44	view →
LGG	DFS	Median	All	0.287	0.487	<.001	44	view →
LIHC	DFS	Tertile	All	0.442	0.622	<.001	40	view →
ACC	DFS	Tertile	All	0.267	0.729	<.001	32	view →
SKCM	OS	Median	III,IV	0.543	0.231	.001	29	view →
UCS	OS	Median	All	0.487	0.235	.018	24	view →
HNSC	OS	Tertile	All	0.291	0.657	<.001	24	view →
MESO	DFS	Median	All	0.310	0.456	.019	22	view →
ESCA	OS	Median	II,III,IV	0.609	0.406	.023	18	view →
BLCA	OS	Median	II,III,IV	0.754	0.659	.020	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SAP30-DT–KICH (DFS)

Open the KICH breakdown →