SAP130

Across TCGA patient cohorts, SAP130 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,129 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAP130-associated proteins across cancer lineages are WDR5, WRNIP1, and DHX9. Each is linked with SAP130 in more than 6 cancer types. Because this analysis shows association rather than direction, both SAP130-to-partner and partner-to-SAP130 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAP130 versus WDR5 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP130→partner) and Y-score (partner→SAP130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR5 →	+0.304	+0.331	<.001	<.001	3	7
LSCC	WRNIP1 →	+0.305	+0.290	<.001	<.001	3	7
LSCC	DHX9 →	+0.249	+0.473	<.001	<.001	3	6
HNSC	GTF3C2 →	+0.327	+0.456	<.001	<.001	3	6
GBM	NONO →	+0.191	+0.307	<.001	<.001	3	6
LSCC	XPO1 →	+0.286	+0.495	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,129 associations by consensus.

SAP130 vs WDR5 — GBM

Explore this scatter interactively →