SAP130

Across TCGA cell cohorts, SAP130 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,687 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAP130-associated GO terms across cancer lineages are Mitotic nuclear division, Chromosome segregation, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with SAP130 in more than 17 cancer types. Because this analysis shows association rather than direction, both SAP130-to-partner and partner-to-SAP130 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear division grouped by SAP130-low versus SAP130-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP130→partner) and Y-score (partner→SAP130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic nuclear division →	+0.096	+0.718	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Chromosome segregation →	+0.101	+0.969	.006	<.001	3	17
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.113	+0.749	.001	<.001	3	17
BONE	Positive regulation of cytokinesis →	+0.130	+0.818	.006	.001	3	17
BONE	Regulation of DNA repair →	+0.078	+0.731	.005	.003	3	17
BONE	Regulation of metaphase plate congression →	+0.199	+0.812	.005	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,687 associations by consensus.

Mitotic nuclear division by SAP130 expression — SOFT_TISSUE

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