SAMSN1

Across TCGA patient cohorts, SAMSN1 mutation is significantly associated with the RNA expression of many other genes, with 3,759 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAMSN1-associated genes across cancer lineages are RNA5SP161, RNU6-178P, and SPECC1P2. Each is linked with SAMSN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAMSN1-to-partner and partner-to-SAMSN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP161 grouped by SAMSN1-low versus SAMSN1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMSN1→partner) and Y-score (partner→SAMSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP161 →	+0.104	+2.332	.002	.004	3	3
BLCA	RNU6-178P →	+0.599	+4.167	<.001	.004	3	2
LIHC	SPECC1P2 →	+0.438	+6.676	<.001	<.001	3	2
UCEC	MIR378H →	+0.451	+1.600	.006	.005	3	2
HNSC	AQP7P4 →	+0.077	+6.111	<.001	.002	3	2
UCEC	PANK4 →	+0.451	+3.069	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

RNA5SP161 by SAMSN1 expression — SKCM

Explore this box plot interactively →