SAMSN1

Across TCGA cell cohorts, SAMSN1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SAMSN1-associated genes across cancer lineages are OR2V1, PRSS58, and TAFA1. Each is linked with SAMSN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMSN1-to-partner and partner-to-SAMSN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2V1 grouped by SAMSN1-low versus SAMSN1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMSN1→partner) and Y-score (partner→SAMSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR2V1 →	+0.017	+4.199	<.001	.007	3	2
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	C14orf180 →	+0.133	+2.892	<.001	.003	3	1
CNS	ZG16 →	+0.044	+4.472	<.001	.004	3	1
CNS	TAS1R2 →	+0.010	+4.643	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

OR2V1 by SAMSN1 expression — BREAST

Explore this box plot interactively →