SAMM50

Across TCGA patient cohorts, SAMM50 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,125 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAMM50-associated proteins across cancer lineages are ATP5MD, ATP5PB, and ATP5PD. Each is linked with SAMM50 in more than 9 cancer types. Because this analysis shows association rather than direction, both SAMM50-to-partner and partner-to-SAMM50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAMM50 versus ATP5MD in UCEC, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMM50→partner) and Y-score (partner→SAMM50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP5MD →	+0.603	+0.582	<.001	<.001	3	10
UCEC	ATP5PB →	+0.665	+0.677	<.001	<.001	3	10
UCEC	ATP5PD →	+0.732	+0.663	<.001	<.001	3	10
HNSC	CHCHD3 →	+0.459	+0.467	<.001	<.001	3	10
UCEC	AFG3L2 →	+0.632	+0.652	<.001	<.001	3	10
UCEC	SLC25A1 →	+0.727	+0.586	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,125 associations by consensus.

SAMM50 vs ATP5MD — UCEC

Explore this scatter interactively →