SAMD4B

Across TCGA pan-cancer cohorts, SAMD4B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SAMD4B data layer compared with 29 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher SAMD4B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SAMD4B expression acts as an unfavorable survival marker.

GBM, LSCC, and UCEC are the cancer types where SAMD4B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.174	0.677	.001	16	view →
LSCC	DFS	Quartile	III,IV	0.370	1.000	.016	11	view →
UCEC	OS	Quartile	II,III,IV	0.522	1.000	.035	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SAMD4B–GBM (OS)

Open the GBM breakdown →