Across TCGA patient cohorts, SAMD11 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SAMD11-associated genes across cancer lineages are GMP, Skeletal muscle, and Neutrophils. Each is linked with SAMD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD11-to-partner and partner-to-SAMD11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD11→partner) and Y-score (partner→SAMD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.103	+4.264	<.001	.024	3	2
SKCM	Skeletal muscle →	+0.058	+2.813	.011	.037	3	1
BLCA	Neutrophils →	+0.013	+3.667	.022	.012	3	1
UCEC	Mesangial cells →	-0.048	-3.258	.002	.010	3	1
SKCM	Erythrocytes →	+0.027	+2.813	.023	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SAMD11 survival (RNA) · tumor vs normal (RNA) · all SAMD11 data types