SAMD1

Across TCGA cell cohorts, SAMD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,530 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SAMD1-associated GO terms across cancer lineages are Negative regulation of transcription initiation-coupled chromatin remodeling, Regulation of DNA repair, and Mitotic chromosome condensation. Each is linked with SAMD1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SAMD1-to-partner and partner-to-SAMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription initiation-coupled chromatin remodeling grouped by SAMD1-low versus SAMD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD1→partner) and Y-score (partner→SAMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of transcription initiation-coupled chromatin remodeling →	+0.219	+0.956	<.001	<.001	3	20
BLOOD_Lymphoma	Regulation of DNA repair →	+0.060	+1.013	<.001	<.001	3	18
BONE	Mitotic chromosome condensation →	+0.174	+0.894	.001	.001	3	18
BONE	Chromosome condensation →	+0.196	+0.939	.005	.006	3	17
BONE	DNA replication checkpoint signaling →	+0.236	+1.155	.001	<.001	3	16
BONE	Regulation of double-strand break repair via homologous recombination →	+0.121	+1.040	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,530 associations by consensus.

Negative regulation of transcription initiation-coupled chromatin remodeling by SAMD1 expression — STOMACH

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