SAGE3P

Across TCGA pan-cancer cohorts, SAGE3P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SAGE3P data layer compared with 12 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SAGE3P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SAGE3P expression acts as an unfavorable survival marker.

BRCA are the cancer types where SAGE3P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.110	0.578	.001	24	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

SAGE3P–BRCA (OS)

Open the BRCA breakdown →