SAAL1

Across TCGA patient cohorts, SAAL1 mutation is significantly associated with the RNA expression of many other genes, with 1,318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAAL1-associated genes across cancer lineages are DNM1P5, MIR615, and OR4A18P. Each is linked with SAAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAAL1-to-partner and partner-to-SAAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNM1P5 grouped by SAAL1-low versus SAAL1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAAL1→partner) and Y-score (partner→SAAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DNM1P5 →	+0.104	+6.810	<.001	<.001	3	2
COAD	MIR615 →	+0.671	+4.693	<.001	.007	3	2
HNSC	OR4A18P →	+0.036	+4.505	<.001	.009	3	2
BLCA	RN7SL22P →	+0.282	+4.973	<.001	.009	3	2
LUSC	MIR3683 →	+0.262	+7.924	<.001	.008	3	2
UCEC	RNU7-29P →	+0.178	+3.219	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,318 associations by consensus.

DNM1P5 by SAAL1 expression — SKCM

Explore this box plot interactively →