S1PR2

Across TCGA patient cohorts, S1PR2 mutation is significantly associated with the RNA expression of many other genes, with 203 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S1PR2-associated genes across cancer lineages are FAM210CP, SNORD65B, and LINC01499. Each is linked with S1PR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both S1PR2-to-partner and partner-to-S1PR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM210CP grouped by S1PR2-low versus S1PR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR2→partner) and Y-score (partner→S1PR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM210CP →	+0.269	+2.319	.004	.006	3	2
PRAD	SNORD65B →	+0.592	+7.939	<.001	.008	3	2
SKCM	LINC01499 →	+0.079	+4.402	<.001	.002	3	2
DLBC	RNU4ATAC2P →	+0.536	+4.874	<.001	.008	3	1
DLBC	PPIAP93 →	+0.957	+4.874	<.001	.008	3	1
UCEC	HMOX1 →	+1.043	+3.595	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 203 associations by consensus.

FAM210CP by S1PR2 expression — UCEC

Explore this box plot interactively →