S1PR2

Across TCGA patient cohorts, S1PR2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S1PR2-associated genes across cancer lineages are Eosinophils, CMP, and Plasma cells. Each is linked with S1PR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both S1PR2-to-partner and partner-to-S1PR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by S1PR2-low versus S1PR2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR2→partner) and Y-score (partner→S1PR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Eosinophils →	+0.054	+3.173	<.001	.049	3	3
STAD	CMP →	+0.048	+3.413	<.001	.034	3	1
UCEC	Plasma cells →	-0.021	-3.034	.040	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Eosinophils by S1PR2 expression — LUSC

Explore this box plot interactively →