S1PR2

Across TCGA cell cohorts, S1PR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,491 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible S1PR2-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Cellular response to type I interferon, and Regulation of intracellular transport. Each is linked with S1PR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both S1PR2-to-partner and partner-to-S1PR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by S1PR2-low versus S1PR2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S1PR2→partner) and Y-score (partner→S1PR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+0.852	<.001	.001	3	10
STOMACH	Cellular response to type I interferon →	+0.092	+0.722	<.001	<.001	3	9
BREAST	Regulation of intracellular transport →	+0.058	+0.845	.001	.001	3	9
STOMACH	Positive regulation of vacuole organization →	+0.095	+0.669	.008	.006	2	9
STOMACH	Regulation of myoblast fusion →	+0.093	+0.554	.008	.007	2	9
LARGE_INTESTINE	Positive regulation of stem cell population maintenance →	+0.053	+0.647	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,491 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by S1PR2 expression — BREAST

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