S100PBP

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, S100PBP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible S100PBP-associated genes across cancer lineages are DUSP21 and IFNA4. Each is linked with S100PBP in more than 1 cancer types. Because this analysis shows association rather than direction, both S100PBP-to-partner and partner-to-S100PBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUSP21 grouped by S100PBP-low versus S100PBP-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100PBP→partner) and Y-score (partner→S100PBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSDUSP21 →+0.032+5.754<.001.00231
CNSIFNA4 →+0.215+5.321<.001.00531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DUSP21 by S100PBP expression — CNS

Box plot of DUSP21 in S100PBP-low vs S100PBP-high samples in CNS.

Explore this box plot interactively →

Exploration