Across TCGA pan-cancer cohorts, S100P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated S100P data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.
The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher S100P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated S100P expression acts as an unfavorable survival marker.
SKCM are the cancer types where S100P Mutation most reproducibly stratifies survival.