S100P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, S100P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated S100P data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher S100P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated S100P expression acts as an unfavorable survival marker.

SKCM are the cancer types where S100P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMOSMedianAll0.2300.781.00415view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

S100P–SKCM (OS)

Kaplan–Meier survival curve for S100P mutant vs wild-type samples in SKCM.

Open the SKCM breakdown →

Exploration