S100P

Across TCGA pan-cancer cohorts, S100P mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated S100P data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher S100P mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated S100P expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where S100P mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	1.000	0.451	.016	15	view →
LUAD	OS	Tertile	All	0.920	1.000	.042	3	view →
LSCC	DFS	Tertile	All	1.000	0.619	.018	2	view →
UCEC	OS	Quartile	All	1.000	0.893	.025	2	view →
HNSC	OS	Tertile	IV	0.904	0.729	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

S100P–CCRCC (OS)

Open the CCRCC breakdown →