S100G

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, S100G mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated S100G data layer compared with 15 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher S100G mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated S100G expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC are the cancer types where S100G mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianII,III,IV0.8600.616.02013view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

S100G–PDAC (DFS)

Kaplan–Meier survival curve for S100G mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration