S100B

Across TCGA patient cohorts, S100B protein abundance is significantly associated with the RNA expression of many other genes, with 12,889 significant associations in total. OV shows the largest number of these associations.

The most reproducible S100B-associated genes across cancer lineages are CD1A, CD1C, and CD1B. Each is linked with S100B in more than 7 cancer types. Because this analysis shows association rather than direction, both S100B-to-partner and partner-to-S100B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100B versus CD1A in LUAD, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100B→partner) and Y-score (partner→S100B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD1A →	+2.633	+1.502	<.001	<.001	3	8
LUAD	CD1C →	+1.404	+1.355	<.001	<.001	3	8
LUAD	CD1B →	+1.046	+1.199	<.001	<.001	3	8
LUAD	CD1E →	+1.639	+1.411	<.001	<.001	3	8
UCEC	SLAMF1 →	+0.890	+0.764	<.001	.001	3	7
HNSC	ARHGAP9 →	+0.708	+0.782	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,889 associations by consensus.

S100B vs CD1A — LUAD

Explore this scatter interactively →