S100B

Across TCGA patient cohorts, S100B mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100B-associated genes across cancer lineages are S6_pS240_S244 and p27_pT198. Each is linked with S100B in more than 1 cancer types. Because this analysis shows association rather than direction, both S100B-to-partner and partner-to-S100B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S6_pS240_S244 grouped by S100B-low versus S100B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100B→partner) and Y-score (partner→S100B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	S6_pS240_S244 →	+0.583	+3.000	.012	.037	3	1
UCEC	p27_pT198 →	+0.145	+3.000	.019	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

S6_pS240_S244 by S100B expression — UCEC

Explore this box plot interactively →