S100A7L2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, S100A7L2 mutation is significantly associated with the RNA expression of many other genes, with 203 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible S100A7L2-associated genes across cancer lineages are UFD1, CACTIN, and MTND5P27. Each is linked with S100A7L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A7L2-to-partner and partner-to-S100A7L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A7L2→partner) and Y-score (partner→S100A7L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECUFD1 →+0.446+3.223.006.00932
SKCMCACTIN →+0.354+2.292.007.00532
SKCMMTND5P27 →+0.008+3.402<.001.00332
UCECRPL23AP90 →+0.436+3.226.001.00231
UCECRNA5SP414 →+1.346+3.255<.001.00131
UCECRNA5SP411 →+2.240+2.978<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 203 associations by consensus.

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