Across TCGA patient cohorts, S100A14 protein abundance is significantly associated with the RNA expression of many other genes, with 11,959 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible S100A14-associated genes across cancer lineages are S100A16, PTK6, and SCEL. Each is linked with S100A14 in more than 7 cancer types. Because this analysis shows association rather than direction, both S100A14-to-partner and partner-to-S100A14 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A14→partner) and Y-score (partner→S100A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	S100A16 →	+1.572	+1.078	<.001	<.001	3	8
OV	PTK6 →	+1.097	+1.106	<.001	.002	3	6
UCEC	SCEL →	+1.413	+0.901	<.001	<.001	3	5
OV	TRIM29 →	+1.491	+1.097	<.001	<.001	3	5
OV	MAL2 →	+1.088	+0.835	<.001	<.001	3	5
LSCC	PSCA →	+1.604	+1.077	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,959 associations by consensus.

Exploration

S100A14 survival (RNA) · tumor vs normal (RNA) · all S100A14 data types