S100A11P6

Across TCGA pan-cancer cohorts, S100A11P6 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated S100A11P6 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher S100A11P6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated S100A11P6 expression acts as an unfavorable survival marker, although some lineages such as LUSC and SKCM show a favorable association.

KIRC, KICH, and DLBC are the cancer types where S100A11P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.633	0.812	.001	120	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
DLBC	OS	Tertile	II,III,IV	0.085	0.865	<.001	81	view →
LUSC	DFS	Tertile	II,III,IV	0.606	0.335	.003	54	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	36	view →
ACC	OS	Tertile	II,III,IV	0.650	0.884	.004	36	view →
LAML	DFS	Tertile	All	0.151	0.599	<.001	30	view →
GBM	OS	Tertile	All	0.064	0.422	<.001	27	view →
STAD	DFS	Tertile	III,IV	0.337	0.544	.011	25	view →
LIHC	OS	Tertile	All	0.622	0.803	.007	21	view →
HNSC	OS	Tertile	IV	0.458	0.709	.007	20	view →
COAD	OS	Tertile	IV	0.123	0.681	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

S100A11P6–KIRC (OS)

Open the KIRC breakdown →