Across TCGA patient cohorts, RYR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,331 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RYR3-associated proteins across cancer lineages are SGCD, LRP1, and CNN3. Each is linked with RYR3 in more than 7 cancer types. Because this analysis shows association rather than direction, both RYR3-to-partner and partner-to-RYR3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RYR3→partner) and Y-score (partner→RYR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SGCD →	+0.621	+0.661	<.001	<.001	3	8
UCEC	LRP1 →	+0.362	+0.582	<.001	<.001	3	8
LSCC	CNN3 →	+0.445	+0.656	<.001	<.001	3	7
COAD	FERMT2 →	+0.668	+0.182	<.001	<.001	3	7
UCEC	ILK →	+0.636	+0.799	<.001	<.001	3	7
UCEC	PDLIM3 →	+0.741	+0.724	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,331 associations by consensus.

Exploration

RYR3 survival (RNA) · tumor vs normal (RNA) · all RYR3 data types