Across TCGA cell cohorts, RYR3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,325 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RYR3-associated genes across cancer lineages are CDKN2B, CIAO3, and SIRT3. Each is linked with RYR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both RYR3-to-partner and partner-to-RYR3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RYR3→partner) and Y-score (partner→RYR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CDKN2B →	+3.503	+0.637	.005	.006	3	3
BLOOD_Leukemia	CIAO3 →	-1.112	-0.628	.001	.005	3	3
BREAST	SIRT3 →	-1.090	-1.256	.004	.002	3	3
BLOOD_Leukemia	ALDH5A1 →	-1.571	-0.874	<.001	<.001	3	3
BLOOD_Leukemia	RAE1 →	-0.620	-0.749	<.001	.001	3	3
BLOOD_Leukemia	GTPBP10 →	-0.611	-0.701	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,325 associations by consensus.

Exploration

RYR3 survival (RNA) · tumor vs normal (RNA) · all RYR3 data types