RYK

Across TCGA patient cohorts, RYK protein abundance is significantly associated with the RNA expression of many other genes, with 1,513 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RYK-associated genes across cancer lineages are RN7SKP185, RPL23P8, and RENBP. Each is linked with RYK in more than 1 cancer types. Because this analysis shows association rather than direction, both RYK-to-partner and partner-to-RYK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RYK versus RN7SKP185 in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RYK→partner) and Y-score (partner→RYK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP185 →	+2.585	+0.310	.006	.002	3	2
UCEC	RPL23P8 →	+1.772	+0.288	.005	.004	3	2
LSCC	RENBP →	-0.970	-0.433	<.001	.003	3	1
LSCC	PLEKHA4 →	-1.020	-0.211	.001	.008	3	1
LSCC	PLBD1 →	-0.805	-0.334	.001	.003	3	1
LSCC	HABP4 →	-0.523	-0.464	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,513 associations by consensus.

RYK vs RN7SKP185 — UCEC

Explore this scatter interactively →