RYK

Across TCGA cell cohorts, RYK RNA expression is significantly associated with the RNA expression of many other genes, with 10,160 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible RYK-associated genes across cancer lineages are SLC25A36, NEPRO, and DNAJC13. Each is linked with RYK in more than 15 cancer types. Because this analysis shows association rather than direction, both RYK-to-partner and partner-to-RYK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RYK versus SLC25A36 in LARGE_INTESTINE, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RYK→partner) and Y-score (partner→RYK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC25A36 →	+1.116	+0.826	<.001	<.001	3	16
OVARY	NEPRO →	+0.820	+1.039	<.001	<.001	3	15
LUNG_NSCLC_LUSC	DNAJC13 →	+1.009	+1.087	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	ASTE1 →	+0.794	+0.883	<.001	<.001	2	15
LUNG_NSCLC_LUSC	ZNF148 →	+1.003	+1.031	<.001	<.001	3	14
LUNG_SCLC	NPHP3 →	+1.260	+0.692	<.001	.002	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,160 associations by consensus.

RYK vs SLC25A36 — LARGE_INTESTINE

Explore this scatter interactively →