RXYLT1-AS1

Across TCGA pan-cancer cohorts, RXYLT1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RXYLT1-AS1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RXYLT1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RXYLT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRC show a favorable association.

LUSC, UCEC, and OV are the cancer types where RXYLT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.597	0.830	<.001	92	view →
UCEC	OS	Tertile	All	0.810	0.892	.005	80	view →
OV	DFS	Quartile	III,IV	0.126	0.210	.007	54	view →
LUAD	OS	Median	II,III,IV	0.832	0.659	.003	37	view →
LIHC	DFS	Tertile	II,III,IV	0.149	0.370	<.001	36	view →
KIRC	DFS	Median	All	0.718	0.529	.013	33	view →
LAML	DFS	Median	All	0.273	0.471	.011	30	view →
DLBC	OS	Median	II,III,IV	0.729	1.000	.008	29	view →
READ	OS	Quartile	III,IV	0.489	0.976	<.001	27	view →
SARC	OS	Tertile	All	0.845	0.639	.007	11	view →
PCPG	DFS	Tertile	All	1.000	0.781	.009	11	view →
COAD	DFS	Tertile	IV	0.255	0.574	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RXYLT1-AS1–LUSC (OS)

Open the LUSC breakdown →