RXYLT1-AS1

Across TCGA pan-cancer cohorts, RXYLT1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RXYLT1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RXYLT1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RXYLT1-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and BLCA are the cancer types where RXYLT1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RXYLT1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	IV	−0.782	<.001	11	view →
KIRC	Male	II,III,IV	−0.322	<.001	9	view →
BLCA	All	All	−0.538	<.001	8	view →
THCA	Male	All	−0.412	<.001	7	view →
UCEC	All	II,III,IV	−0.719	<.001	6	view →
BRCA	All	III,IV	−0.558	<.001	6	view →
LUSC	Female	III,IV	−0.860	<.001	5	view →
KIRP	Female	II,III,IV	−0.450	.006	4	view →
STAD	All	All	−0.340	.005	3	view →
PRAD	All	All	−0.463	<.001	2	view →
READ	All	All	−0.362	.018	2	view →
LUAD	All	All	−0.149	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RXYLT1-AS1–KICH

Open the KICH breakdown →