Across TCGA patient cohorts, RXRB mutation is significantly associated with the RNA expression of many other genes, with 3,654 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RXRB-associated genes across cancer lineages are RN7SL530P, RNU6-12P, and RNA5SP411. Each is linked with RXRB in more than 2 cancer types. Because this analysis shows association rather than direction, both RXRB-to-partner and partner-to-RXRB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RXRB→partner) and Y-score (partner→RXRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL530P →	+1.065	+3.993	<.001	.005	3	3
COAD	RNU6-12P →	+0.644	+4.428	<.001	.002	3	3
UCEC	RNA5SP411 →	+0.943	+1.756	<.001	.005	3	2
UCEC	RN7SL478P →	+0.195	+1.975	.001	.001	3	2
LIHC	RNA5SP351 →	+0.375	+6.593	<.001	<.001	3	2
LUAD	KRTAP9-12P →	+0.617	+4.453	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,654 associations by consensus.

Exploration

RXRB survival (RNA) · tumor vs normal (RNA) · all RXRB data types