RXFP4

Across TCGA patient cohorts, RXFP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,302 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RXFP4-associated proteins across cancer lineages are VPS13C_S737, TMPO_S385, and ARHGEF2. Each is linked with RXFP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both RXFP4-to-partner and partner-to-RXFP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RXFP4 versus VPS13C_S737 in HNSC, with a Pearson correlation of -0.17.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RXFP4→partner) and Y-score (partner→RXFP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VPS13C_S737 →	-0.550	-0.362	<.001	.003	3	4
CCRCC	TMPO_S385 →	+1.320	+0.667	.003	.005	3	4
UCEC	ARHGEF2 →	+0.340	+0.831	<.001	<.001	3	4
CCRCC	SLC9A3R1_S269 →	-0.782	-0.586	<.001	<.001	3	4
LUAD	CLASP2_S14 →	-0.502	-0.556	<.001	<.001	3	4
CCRCC	EIF4EBP2_S65 →	+0.693	+0.552	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,302 associations by consensus.

RXFP4 vs VPS13C_S737 — HNSC

Explore this scatter interactively →