RXFP2

Across TCGA patient cohorts, RXFP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,942 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RXFP2-associated GO terms across cancer lineages are Actin polymerization or depolymerization, Regulation of protein polymerization, and Myeloid leukocyte differentiation. Each is linked with RXFP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both RXFP2-to-partner and partner-to-RXFP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin polymerization or depolymerization grouped by RXFP2-low versus RXFP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RXFP2→partner) and Y-score (partner→RXFP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Actin polymerization or depolymerization →	+0.055	+0.132	<.001	<.001	3	15
ESCA	Regulation of protein polymerization →	+0.064	+0.142	<.001	<.001	3	15
ESCA	Myeloid leukocyte differentiation →	+0.064	+0.155	<.001	.002	3	15
STAD	Fat cell differentiation →	+0.045	+0.111	<.001	<.001	3	15
STAD	Regulation of actin filament organization →	+0.056	+0.147	<.001	<.001	3	15
ESCA	Response to transforming growth factor beta →	+0.078	+0.130	<.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,942 associations by consensus.

Actin polymerization or depolymerization by RXFP2 expression — STAD

Explore this box plot interactively →