RWDD4

Across TCGA cell cohorts, RWDD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,291 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RWDD4-associated GO terms across cancer lineages are DAMP biosynthetic process, Purine deoxyribonucleoside monophosphate biosynthetic process, and Mitochondrial DNA replication. Each is linked with RWDD4 in more than 12 cancer types. Because this analysis shows association rather than direction, both RWDD4-to-partner and partner-to-RWDD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAMP biosynthetic process grouped by RWDD4-low versus RWDD4-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD4→partner) and Y-score (partner→RWDD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	DAMP biosynthetic process →	+0.146	+0.764	<.001	<.001	3	13
KIDNEY	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.146	+0.764	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitochondrial DNA replication →	+0.113	+1.096	.001	<.001	3	11
LUNG_NSCLC_LUSC	Depurination →	+0.130	+0.760	.001	.003	3	11
OVARY	Error-prone translesion synthesis →	+0.106	+0.847	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of sister chromatid segregation →	+0.090	+0.939	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,291 associations by consensus.

DAMP biosynthetic process by RWDD4 expression — KIDNEY

Explore this box plot interactively →