RWDD4

Across TCGA pan-cancer cohorts, RWDD4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RWDD4 data layer compared with 4 for mutation status and 8 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RWDD4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RWDD4 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRC show a favorable association.

MESO, LGG, and CESC are the cancer types where RWDD4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.283	0.477	.002	53	view →
LGG	DFS	Median	All	0.768	0.895	<.001	43	view →
CESC	DFS	Tertile	IV	0.235	0.746	.006	38	view →
LIHC	DFS	Median	All	0.472	0.630	.001	38	view →
ACC	DFS	Tertile	All	0.266	0.740	<.001	34	view →
SCLC	OS	Quartile	All	0.647	0.844	.001	32	view →
LUAD	OS	Tertile	All	0.302	0.480	.007	18	view →
OV	OS	Median	IV	0.783	0.483	<.001	18	view →
KIRC	OS	Median	All	0.693	0.561	.002	17	view →
KIRP	DFS	Tertile	All	0.931	0.583	.003	16	view →
UVM	DFS	Quartile	III,IV	0.095	1.000	.006	14	view →
BRCA	DFS	Quartile	All	0.965	0.915	.010	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RWDD4–MESO (OS)

Open the MESO breakdown →