RWDD1

Across TCGA pan-cancer cohorts, RWDD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RWDD1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RWDD1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RWDD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and COAD show a favorable association.

CCRCC, COAD, and PDAC are the cancer types where RWDD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	IV	0.908	0.229	.010	24	view →
COAD	DFS	Median	IV	1.000	0.605	.043	6	view →
PDAC	DFS	Quartile	III,IV	1.000	0.500	.040	5	view →
LSCC	DFS	Tertile	All	1.000	0.603	.030	3	view →
HNSC	OS	Median	III,IV	1.000	0.449	.023	2	view →
GBM	DFS	Quartile	All	0.231	0.421	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RWDD1–CCRCC (DFS)

Open the CCRCC breakdown →