RWDD1

Across TCGA pan-cancer cohorts, RWDD1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RWDD1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RWDD1 RNA is repressed in tumor relative to normal tissue. In most cancer types RWDD1 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, LIHC, and KICH are the cancer types where RWDD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RWDD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.524	<.001	9	view →
LIHC	All	II,III,IV	+0.540	<.001	8	view →
KICH	Female	II,III,IV	−1.187	<.001	7	view →
THCA	All	All	−0.239	<.001	7	view →
BLCA	All	III,IV	−0.491	.006	6	view →
BRCA	All	All	−0.235	<.001	6	view →
CHOL	All	All	+0.976	.001	4	view →
UCEC	All	All	−0.540	.004	2	view →
PRAD	All	All	−0.213	.021	2	view →
LUSC	All	All	−0.161	.047	2	view →
HNSC	All	IV	+0.306	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RWDD1–LUAD

Open the LUAD breakdown →