RWDD1

Across TCGA patient cohorts, RWDD1 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RWDD1-associated genes across cancer lineages are PCBD1, METTL1P1, and UFD1. Each is linked with RWDD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RWDD1-to-partner and partner-to-RWDD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCBD1 grouped by RWDD1-low versus RWDD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD1→partner) and Y-score (partner→RWDD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCBD1 →	+0.646	+3.202	.001	.009	3	1
UCEC	METTL1P1 →	+0.165	+3.267	.008	.001	3	1
UCEC	UFD1 →	+0.517	+3.223	.001	.009	3	1
UCEC	RNA5SP414 →	+0.643	+2.670	<.001	.009	3	1
UCEC	RNA5SP411 →	+1.433	+2.978	<.001	.001	3	1
UCEC	RNA5SP412 →	+0.915	+2.967	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

PCBD1 by RWDD1 expression — UCEC

Explore this box plot interactively →