RUVBL1

Across TCGA cell cohorts, RUVBL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,938 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RUVBL1-associated GO terms across cancer lineages are RNA localization to Cajal body, Telomerase RNA localization to Cajal body, and Telomerase RNA localization. Each is linked with RUVBL1 in more than 19 cancer types. Because this analysis shows association rather than direction, both RUVBL1-to-partner and partner-to-RUVBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization to Cajal body grouped by RUVBL1-low versus RUVBL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RUVBL1→partner) and Y-score (partner→RUVBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA localization to Cajal body →	+0.140	+1.352	.002	<.001	3	20
URINARY_TRACT	Telomerase RNA localization to Cajal body →	+0.142	+0.836	<.001	<.001	3	20
URINARY_TRACT	Telomerase RNA localization →	+0.142	+0.836	<.001	<.001	3	20
BONE	RNA localization to nucleus →	+0.140	+1.352	.002	<.001	3	20
OESOPHAGUS	Ribosomal small subunit biogenesis →	+0.112	+0.976	<.001	<.001	3	19
BONE	DNA replication initiation →	+0.220	+1.184	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,938 associations by consensus.

RNA localization to Cajal body by RUVBL1 expression — BONE

Explore this box plot interactively →