RUSF1

Across TCGA cell cohorts, RUSF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,714 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible RUSF1-associated GO terms across cancer lineages are Negative regulation of autophagy, Cilium or flagellum-dependent cell motility, and Regulation of macroautophagy. Each is linked with RUSF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both RUSF1-to-partner and partner-to-RUSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagy grouped by RUSF1-low versus RUSF1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSF1→partner) and Y-score (partner→RUSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.099	+1.127	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.132	-0.959	<.001	<.001	3	16
OESOPHAGUS	Regulation of macroautophagy →	+0.088	+1.047	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.132	-0.959	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.137	-0.959	<.001	<.001	3	16
BLOOD_Myeloma	Negative regulation of macroautophagy →	+0.093	+0.976	.001	.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,714 associations by consensus.

Negative regulation of autophagy by RUSF1 expression — UPPER_AERODIGESTIVE_TRACT

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