RUSF1

Across TCGA pan-cancer cohorts, RUSF1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RUSF1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RUSF1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RUSF1 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

KIRP, COAD, and THCA are the cancer types where RUSF1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RUSF1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	+1.186	<.001	10	view →
COAD	Male	III,IV	+0.747	<.001	10	view →
THCA	Male	III,IV	−0.967	<.001	8	view →
LUAD	Female	All	+0.362	<.001	7	view →
BLCA	Female	III,IV	+0.728	<.001	6	view →
BRCA	All	II,III,IV	+0.480	<.001	6	view →
UCEC	All	All	−0.644	.004	4	view →
STAD	Male	All	+0.576	.010	4	view →
HNSC	All	All	+0.469	.003	4	view →
KIRC	Female	All	+0.439	.001	4	view →
CHOL	All	II,III,IV	+1.160	.025	2	view →
KICH	Female	All	−0.433	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RUSF1–KIRP

Open the KIRP breakdown →