RUSC1

Across TCGA cell cohorts, RUSC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,618 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RUSC1-associated genes across cancer lineages are TMEM37, MX2, and ZNF621. Each is linked with RUSC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RUSC1-to-partner and partner-to-RUSC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RUSC1 versus TMEM37 in BLOOD_Leukemia, with a Pearson correlation of -0.20.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSC1→partner) and Y-score (partner→RUSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TMEM37 →	-0.132	-0.633	.003	.002	3	4
SKIN	MX2 →	-3.752	-0.906	<.001	.004	3	4
SKIN	ZNF621 →	+0.901	+1.033	.003	.001	3	4
SKIN	CSNK1E →	+0.763	+1.135	.008	.004	3	4
BLOOD_Myeloma	ZFAND1 →	+1.739	+1.870	.004	.005	3	4
LARGE_INTESTINE	UBQLN2 →	-0.904	-1.084	.003	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,618 associations by consensus.

RUSC1 vs TMEM37 — BLOOD_Leukemia

Explore this scatter interactively →